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中国药科大学-化学学院

中国药科大学-化学学院

林爱俊

发布时间：2026-10-27浏览次数：23文章来源：化学学院

简介：

林爱俊，中国药科大学化学学院有机化学系教授，博士生导师。2005-2011年，南京大学化学化工学院有机化学专业硕/博连读，获博士学位。2011-2012年，南京大学化学化工学院/生命科学学院博士后。2012-2014年，美国德州农工大学（TexasA&MUniversity）化学系博士后。2014-2018年，中国药科大学药学院药物化学系，副教授。2018-2026年，中国药科大学药学院药物化学系，教授。2026年10月起，中国药科大学化学学院，教授。至今以通讯作者在Nat.Commun.、J. Am. Chem.Soc.、Angew.Chem. Int. Ed.、ACSCatal.、GreenChem.、CCSChem.、Sci.China Chem.、Org.Lett.等期刊上发表论文100余篇。


研究方向：

不饱和烃转化应用研究；功能手性杂环/桥环化合物合成应用研究


合作老师：

姚和权教授


代表性文章：

1.Zhong, Jing;+Li, Mengxian;+Ma, Jiao; Zhang, Zimo; Fang, Hao; Gao, Shang; Lin,Aijun;* Yao, Hequan.*Copper-Catalyzed Enantioselective Radical Desymmetrizing Cyclizationof Cyclopentenes: Access to Chiral 2-Azabicyclo[2.2.1]Heptan-3-ones.Angew. Chem. Int. Ed.2026,65, e21476.

2. Li, Qiuyu;+Wu, Ruixue;+Wu, Tianbao;+Wei, Renkang; Li, Zhijiao; Gao, Shang; Wang, Minyan;* Yao, Hequan;*Lin, Aijun.*Palladium-Catalyzed Asymmetric Sequential Hydroalkylation andHydroamination of 1,3-Enynes with 3-Hydroxyindoles. GreenChem. 2026,28,3232–3242.

3.Zhong, Jing;+Li, Mengxian;+Wu, Changhui;+Li, Hui;+Dong, Hongyue; Che, Chunchen; Lin,Aijun;* Yao, Hequan.*Catalytic AsymmetricTandem Heck/Sonogashira Reaction Enabling Access to Versatile ChiralBridged Ring Scaffolds. Nat.Commun. 2025,16, 11373.

4. Chen, Long;+Zhou, Hengrui;+Xue, Yiji; Kong, Lingyu; Wang, Yi; Han, Xuyao; Yao, Hequan;* Lin,Aijun.* Synthesis ofChiral Polycyclic Indoles via Pd(II)-Catalyzed Sequential Cyclizationand Carbonylation, ACSCatal. 2024,14,8739-8747.

5.Li, Qiuyu;+Li, Jiajia;+Zhang, Jie; Wu, Shu; Zhang, Yu; Lin,Aijun;* Yao, Hequan.*Enantioselective Synthesis of Bicyclo[3.2.1]octadienes via PalladiumCatalyzed Intramolecular Alkene-Alkyne Coupling Reaction.Angew. Chem. Int. Ed. 2023,62, e202313404.

6.Li, Qiuyu;+Zhang, Yunchu;+Liu, Pengyun; Zhong, Jing; Gong, Baihui; Yao, Hequan;* Lin,Aijun.* Pd-CatalyzedAsymmetric 5-exo-trig Cyclization/Cyclopropanation/Carbonylation of1,6-Enynes for the Construction of Chiral 3-Azabicyclo[3.1.0]hexanes.Angew. Chem. Int. Ed.2023,62,e202211988.

7.Li, Qiuyu;+Fang Xinxin;+Pan Rui; Yao Hequan;* LinAijun.*Palladium-Catalyzed Asymmetric Sequential Hydroamination of1,3-Enynes: Enantioselective Syntheses of Chiral Imidazolidinones.J. Am. Chem.Soc. 2022,144,11364-11376.

8.Zhang, Dongquan;Li, Miaomiao; Li, Jiajia;Lin, Aijun;* Yao,Hequan.* Rhodium-catalyzed Intermolecular Enantioselective Alder–eneType Reaction of Cyclopentenes with Silylacetylenes. Nat.Commun. 2021,12,6627.

9.Yuan, Zhenbo; Zeng,Yuye; Feng, Ziwen; Guan, Zhe; Lin,Aijun;* Yao, Hequan.*Constructing Chiral Bicyclo[3.2.1]octanes via Palladium-catalyzedAsymmetric Tandem Heck/Carbonylation Desymmetrization ofCyclopentenes. Nat.Commun. 2020,11,2544.

10.Yuan, Zhenbo; Feng,Ziwen; Zeng, Yuye; Zhao, Xiaobin; Lin,Aijun;* Yao, Hequan.*Palladium-Catalyzed Asymmetric Intramolecular Reductive HeckDesymmetrization of Cyclopentenes: Access to ChiralBicyclo[3.2.1]octanes. Angew.Chem. Int. Ed. 2019,58,2884–2888.


代表性基金项目：

1.催化不对称连续氢官能化/环化构建手性氮杂环化合物研究，22678620，国自然面上项目，在研。